Deficiency in Serine Protease Inhibitor Neuroserpin Exacerbates Ischemic Brain Injury by Increased Postischemic Inflammation

The only approved pharmacological treatment for ischemic stroke is intravenous administration of plasminogen activator (tPA) to re-canalize the occluded cerebral vessel. Not only reperfusion but also tPA itself can induce an inflammatory response. Microglia are the innate immune cells of the central...

Descripción completa

Detalles Bibliográficos
Autores principales: Gelderblom, Mathias, Neumann, Melanie, Ludewig, Peter, Bernreuther, Christian, Krasemann, Susanne, Arunachalam, Priyadharshini, Gerloff, Christian, Glatzel, Markus, Magnus, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643909/
https://www.ncbi.nlm.nih.gov/pubmed/23658802
http://dx.doi.org/10.1371/journal.pone.0063118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643909/
https://www.ncbi.nlm.nih.gov/pubmed/23658802
http://dx.doi.org/10.1371/journal.pone.0063118

Ejemplares similares