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Acetylcholinesterase Inhibitors Reduce Neuroinflammation and -Degeneration in the Cortex and Hippocampus of a Surgery Stress Rat Model

Exogenous stress like tissue damage and pathogen invasion during surgical trauma could lead to a peripheral inflammatory response and induce neuroinflammation, which can result in postoperative cognitive dysfunction (POCD). The cholinergic anti-inflammatory pathway is a neurohumoral mechanism that p...

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Detalles Bibliográficos
Autores principales: Kalb, Alexander, von Haefen, Clarissa, Sifringer, Marco, Tegethoff, Annalena, Paeschke, Nadine, Kostova, Mariya, Feldheiser, Aarne, Spies, Claudia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643957/
https://www.ncbi.nlm.nih.gov/pubmed/23671623
http://dx.doi.org/10.1371/journal.pone.0062679