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Amelioration of IFN-γ and TNF-α-Induced Intestinal Epithelial Barrier Dysfunction by Berberine via Suppression of MLCK-MLC Phosphorylation Signaling Pathway

Intestinal barrier dysfunction occurs in many intestinal diseases, in which proinflammatory cytokines play critical roles. However, researchers are still on the way to defining the underlying mechanisms and to evaluate therapeutic strategies for restoring intestinal barrier function. Berberine, a dr...

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Detalles Bibliográficos
Autores principales: Cao, Min, Wang, Pei, Sun, Chunhong, He, Wen, Wang, Fengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643960/
https://www.ncbi.nlm.nih.gov/pubmed/23671580
http://dx.doi.org/10.1371/journal.pone.0061944