Enhancement of Proteolytic Activity of a Thermostable Papain-Like Protease by Structure-Based Rational Design

Ervatamins (A, B and C) are papain-like cysteine proteases from the plant Ervatamia coronaria. Among Ervatamins, Ervatamin-C is a thermostable protease, but it shows lower catalytic efficiency. In contrast, Ervatamin-A which has a high amino acid sequence identity (∼90%) and structural homology (Cα...

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Detalles Bibliográficos
Autores principales: Dutta, Sruti, Dattagupta, Jiban Kanti, Biswas, Sampa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643963/
https://www.ncbi.nlm.nih.gov/pubmed/23671614
http://dx.doi.org/10.1371/journal.pone.0062619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643963/
https://www.ncbi.nlm.nih.gov/pubmed/23671614
http://dx.doi.org/10.1371/journal.pone.0062619

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