Cargando…

Mechanical unzipping and rezipping of a single SNARE complex reveals hysteresis as a force-generating mechanism

Formation of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex provides mechanical thrust for membrane fusion, but its molecular mechanism is still unclear. Here using magnetic tweezers, we observe mechanical responses of a single neuronal SNARE complex under...

Descripción completa

Detalles Bibliográficos
Autores principales: Min, Duyoung, Kim, Kipom, Hyeon, Changbong, Hoon Cho, Yong, Shin, Yeon-Kyun, Yoon, Tae-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644077/
https://www.ncbi.nlm.nih.gov/pubmed/23591872
http://dx.doi.org/10.1038/ncomms2692