A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel

Voltage-gated potassium channels elicit membrane hyperpolarization through voltage-sensor domains that regulate the conductive status of the pore domain. To better understand the inherent basis for the open-closed equilibrium in these channels, we undertook an atomistic scan using synthetic fluorina...

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Detalles Bibliográficos
Autores principales: Pless, Stephan A., Niciforovic, Ana P., Galpin, Jason D., Nunez, John-Jose, Kurata, Harley T., Ahern, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644096/
https://www.ncbi.nlm.nih.gov/pubmed/23653196
http://dx.doi.org/10.1038/ncomms2761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644096/
https://www.ncbi.nlm.nih.gov/pubmed/23653196
http://dx.doi.org/10.1038/ncomms2761

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