Sub-acute administration of (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate induces toxicity and oxidative stress in mice: unexpected effects of N-acetylcysteine

The organic tellurium compound (S)-dimethyl 2-(3-(phenyltellanyl) propanamide) succinate (TeAsp) exhibits thiol-peroxidase activity that could potentially offer protection against oxidative stress. However, data from the literature show that tellurium is a toxic agent to rodents. In order to mitigat...

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Detalles Bibliográficos
Autores principales: Meinerz, Daiane F, Comparsi, Bruna, Allebrandt, Josiane, Mariano, Douglas Oscar Ceolin, dos Santos, Danúbia B, Zemolin, Ana Paula Pegoraro, Farina, Marcelo, Dafre, Luiz Alcir, Rocha, João B T, Posser, Thaís, Franco, Jeferson L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644195/
https://www.ncbi.nlm.nih.gov/pubmed/23658858
http://dx.doi.org/10.1186/2193-1801-2-182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644195/
https://www.ncbi.nlm.nih.gov/pubmed/23658858
http://dx.doi.org/10.1186/2193-1801-2-182

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