Cargando…
Sub-acute administration of (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate induces toxicity and oxidative stress in mice: unexpected effects of N-acetylcysteine
The organic tellurium compound (S)-dimethyl 2-(3-(phenyltellanyl) propanamide) succinate (TeAsp) exhibits thiol-peroxidase activity that could potentially offer protection against oxidative stress. However, data from the literature show that tellurium is a toxic agent to rodents. In order to mitigat...
Autores principales: | Meinerz, Daiane F, Comparsi, Bruna, Allebrandt, Josiane, Mariano, Douglas Oscar Ceolin, dos Santos, Danúbia B, Zemolin, Ana Paula Pegoraro, Farina, Marcelo, Dafre, Luiz Alcir, Rocha, João B T, Posser, Thaís, Franco, Jeferson L |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644195/ https://www.ncbi.nlm.nih.gov/pubmed/23658858 http://dx.doi.org/10.1186/2193-1801-2-182 |
Ejemplares similares
-
Cytotoxicity and Genotoxicity Evaluation of Organochalcogens in Human Leucocytes: A Comparative Study between Ebselen, Diphenyl Diselenide, and Diphenyl Ditelluride
por: Caeran Bueno, Diones, et al.
Publicado: (2013) -
Differential genotoxicity of diphenyl diselenide (PhSe)(2) and diphenyl ditelluride (PhTe)(2)
por: Meinerz, Daiane Francine, et al.
Publicado: (2014) -
4-(3-Chloro-2,2-dimethylpropanamido)benzenesulfonamide
por: Yalçın, Şerife Pınar, et al.
Publicado: (2012) -
Development and In Vivo Assessment of 4-Phenyltellanyl-7-chloroquinoline-loaded Polymeric Nanocapsules in Alzheimer’s Disease Models
por: Funguetto-Ribeiro, Ana Cláudia, et al.
Publicado: (2023) -
Hyperosmotic Stress Initiates AMPK-Independent Autophagy and AMPK- and Autophagy-Independent Depletion of Thioredoxin 1 and Glyoxalase 2 in HT22 Nerve Cells
por: Dafre, Alcir Luiz, et al.
Publicado: (2019)