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TRPV1-mediated UCP2 upregulation ameliorates hyperglycemia-induced endothelial dysfunction
BACKGROUND: Diabetic cardiovascular complications are characterised by oxidative stress-induced endothelial dysfunction. Uncoupling protein 2 (UCP2) is a regulator of mitochondrial reactive oxygen species (ROS) generation and can antagonise oxidative stress, but approaches that enhance the activity...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644255/ https://www.ncbi.nlm.nih.gov/pubmed/23607427 http://dx.doi.org/10.1186/1475-2840-12-69 |