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TRPV1-mediated UCP2 upregulation ameliorates hyperglycemia-induced endothelial dysfunction

BACKGROUND: Diabetic cardiovascular complications are characterised by oxidative stress-induced endothelial dysfunction. Uncoupling protein 2 (UCP2) is a regulator of mitochondrial reactive oxygen species (ROS) generation and can antagonise oxidative stress, but approaches that enhance the activity...

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Detalles Bibliográficos
Autores principales:	Sun, Jing, Pu, Yunfei, Wang, Peijian, Chen, Sijiao, Zhao, Yu, Liu, Chan, Shang, Qianhui, Zhu, Zhiming, Liu, Daoyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644255/ https://www.ncbi.nlm.nih.gov/pubmed/23607427 http://dx.doi.org/10.1186/1475-2840-12-69

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