Vascular E-selectin expression correlates with CD8 lymphocyte infiltration and improved outcome in Merkel cell carcinoma

Merkel cell carcinoma (MCC) is an aggressive, polyomavirus-linked skin cancer. While CD8 lymphocyte infiltration into the tumor is strongly correlated with improved survival, these cells are absent or sparse in most MCCs. We investigated whether specific mechanisms of T-cell migration may be commonl...

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Detalles Bibliográficos
Autores principales: Afanasiev, Olga K., Nagase, Kotaro, Simonson, William, Vandeven, Natalie, Blom, Astrid, Koelle, David M., Clark, Rachael, Nghiem, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644376/
https://www.ncbi.nlm.nih.gov/pubmed/23353989
http://dx.doi.org/10.1038/jid.2013.36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644376/
https://www.ncbi.nlm.nih.gov/pubmed/23353989
http://dx.doi.org/10.1038/jid.2013.36

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