Parkinson’s disease-associated mutations in DJ-1 modulate its dimerization in living cells

Mutations in the protein DJ-1 cause recessive forms of early onset familial Parkinson’s disease (PD). To date, most of the causative mutations studied destabilize formation of DJ-1 homodimers, which appears to be closely linked to its normal function in oxidative stress and other cellular processes....

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Detalles Bibliográficos
Autores principales: Repici, Mariaelena, Straatman, Kornelis R., Balduccio, Nadia, Enguita, Francisco J., Outeiro, Tiago F., Giorgini, Flaviano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644405/
https://www.ncbi.nlm.nih.gov/pubmed/23183826
http://dx.doi.org/10.1007/s00109-012-0976-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644405/
https://www.ncbi.nlm.nih.gov/pubmed/23183826
http://dx.doi.org/10.1007/s00109-012-0976-y

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