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Suppression of the Rho/Rho-Kinase Pathway and Prevention of Cerebral Vasospasm by Combination Treatment with Statin and Fasudil After Subarachnoid Hemorrhage in Rabbit

The Rho/Rho-kinase pathway is considered important in the pathogenesis of sustained smooth muscle cell contraction during cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH). The aims of this study were to investigate whether combination treatment, with pitavastatin as an inhibitor of...

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Detalles Bibliográficos
Autores principales: Naraoka, Masato, Munakata, Akira, Matsuda, Naoya, Shimamura, Norihito, Ohkuma, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644406/
https://www.ncbi.nlm.nih.gov/pubmed/23658597
http://dx.doi.org/10.1007/s12975-012-0247-9