Role of DNA Repair Pathways in Response to Zidovudine-induced DNA Damage in Immortalized Human Liver THLE2 Cells

The nucleoside reverse transcriptase inhibitor zidovudine (3’-azido-3’-dexoythymidine, AZT) can be incorporated into DNA and cause DNA damage. Previously, we determined that the human hepatocellular carcinoma HepG2 cells are more susceptible to AZT-induced toxicities than the immortalized normal hum...

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Detalles Bibliográficos
Autores principales: Wu, Qiangen, Beland, Frederick A., Chang, Ching-Wei, Fang, Jia-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Master Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644411/
https://www.ncbi.nlm.nih.gov/pubmed/23675285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644411/
https://www.ncbi.nlm.nih.gov/pubmed/23675285

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