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Endogenous cholinergic tone modulates spontaneous network level neuronal activity in primary cortical cultures grown on multi-electrode arrays

BACKGROUND: Cortical cultures grown long-term on multi-electrode arrays (MEAs) are frequently and extensively used as models of cortical networks in studies of neuronal firing activity, neuropharmacology, toxicology and mechanisms underlying synaptic plasticity. However, in contrast to the predomina...

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Detalles Bibliográficos
Autores principales: Hammond, Mark W, Xydas, Dimitris, Downes, Julia H, Bucci, Giovanna, Becerra, Victor, Warwick, Kevin, Constanti, Andrew, Nasuto, Slawomir J, Whalley, Benjamin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644495/
https://www.ncbi.nlm.nih.gov/pubmed/23530974
http://dx.doi.org/10.1186/1471-2202-14-38