Aptamers and Their Potential to Selectively Target Aspects of EGF, Wnt/β-Catenin and TGFβ–Smad Family Signaling

The smooth identification and low-cost production of highly specific agents that interfere with signaling cascades by targeting an active domain in surface receptors, cytoplasmic and nuclear effector proteins, remain important challenges in biomedical research. We propose that peptide aptamers can p...

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Detalles Bibliográficos
Autores principales: Conidi, Andrea, van den Berghe, Veronique, Huylebroeck, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645661/
https://www.ncbi.nlm.nih.gov/pubmed/23531534
http://dx.doi.org/10.3390/ijms14046690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645661/
https://www.ncbi.nlm.nih.gov/pubmed/23531534
http://dx.doi.org/10.3390/ijms14046690

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