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Synthesis of 1-isopropyl-3-acyl-5-methyl-benzimidazolone Derivatives and Their Antimicrobial Activity

A series of N-acylated analogues of 1-isopropyl-3-acyl-5-methyl-benzimidazolone were synthesized. Bioassay results indicated that analogues 5-07 and 5-19 exhibited the most potency against Bacillus cereus, Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Analogu...

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Detalles Bibliográficos
Autores principales: Xu, Nan, Yang, Chunnan, Gan, Xinqi, Wei, Shaopeng, Ji, Zhiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645665/
https://www.ncbi.nlm.nih.gov/pubmed/23531538
http://dx.doi.org/10.3390/ijms14046790