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Epigenetic Silencing of DKK3 in Medulloblastoma

Medulloblastoma (MB) is a malignant pediatric brain tumor arising in the cerebellum consisting of four distinct subgroups: WNT, SHH, Group 3 and Group 4, which exhibit different molecular phenotypes. We studied the expression of Dickkopf (DKK) 1–4 family genes, inhibitors of the Wnt signaling cascad...

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Detalles Bibliográficos
Autores principales: Valdora, Francesca, Banelli, Barbara, Stigliani, Sara, Pfister, Stefan M., Moretti, Stefano, Kool, Marcel, Remke, Marc, Bai, Alfa H.C., Brigati, Claudio, Hielscher, Thomas, Romani, Massimo, Servidei, Tiziana, Zollo, Massimo, Cinalli, Giuseppe, Oberthuer, André, Tonini, Gian Paolo, Coco, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645699/
https://www.ncbi.nlm.nih.gov/pubmed/23567267
http://dx.doi.org/10.3390/ijms14047492