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Environmental Oxygen Tension Regulates the Energy Metabolism and Self-Renewal of Human Embryonic Stem Cells

Energy metabolism is intrinsic to cell viability but surprisingly has been little studied in human embryonic stem cells (hESCs). The current study aims to investigate the effect of environmental O(2) tension on carbohydrate utilisation of hESCs. Highly pluripotent hESCs cultured at 5% O(2) consumed...

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Detalles Bibliográficos
Autores principales: Forristal, Catherine E., Christensen, David R., Chinnery, Fay E., Petruzzelli, Raffaella, Parry, Kate L., Sanchez-Elsner, Tilman, Houghton, Franchesca D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645991/
https://www.ncbi.nlm.nih.gov/pubmed/23671606
http://dx.doi.org/10.1371/journal.pone.0062507