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A Novel Approach for Characterizing Microsatellite Instability in Cancer Cells

Microsatellite instability (MSI) is characterized by the expansion or contraction of DNA repeat tracts as a consequence of DNA mismatch repair deficiency (MMRD). Accurate detection of MSI in cancer cells is important since MSI is associated with several cancer subtypes and can help inform therapeuti...

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Detalles Bibliográficos
Autores principales: Lu, Yuheng, Soong, T. David, Elemento, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646030/
https://www.ncbi.nlm.nih.gov/pubmed/23671654
http://dx.doi.org/10.1371/journal.pone.0063056