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Selective constraint and the evolution of the RNA Polymerase II C-Terminal Domain

The C-Terminal Domain (CTD) of the large subunit (Rpb1) of RNA Polymerase II has a Tyrosine-Serine-Proline-Threonine-Serine-Proline-Serine repeat structure in many eukaryotes. Chemical modifications of these residues play a central role in the regulation and coordination of the events of transcripti...

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Detalles Bibliográficos
Autores principales: Stump, Aram D., Ostrozhynska, Khrystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646058/
https://www.ncbi.nlm.nih.gov/pubmed/23412361
http://dx.doi.org/10.4161/trns.23305