Anti-angiogenic Effects of Metformin, an AMPK Activator, on Human Umbilical Vein Endothelial Cells and on Granulation Tissue in Rat

OBJECTIVE(S): Metformin is well known for activation of AMP-activated protein kinase (AMPK). AMPK activation inhibits mammalian target of rapamycin (mTOR) as a key signaling process in cell proliferation. Recent epidemiological studies demonstrate that metformin lowers the risk for several types of...

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Detalles Bibliográficos
Autores principales: Soraya, Hamid, Esfahanian, Nilufar, Shakiba, Yadollah, Ghazi-Khansari, Mahmood, Nikbin, Behroz, Hafezzadeh, Hasan, Maleki Dizaji, Nasrin, Garjani, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646233/
https://www.ncbi.nlm.nih.gov/pubmed/23653852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646233/
https://www.ncbi.nlm.nih.gov/pubmed/23653852

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