A holistic evolutionary and structural study of flaviviridae provides insights into the function and inhibition of HCV helicase

Viral RNA helicases are involved in duplex unwinding during the RNA replication of the virus. It is suggested that these helicases represent very promising antiviral targets. Viruses of the flaviviridae family are the causative agents of many common and devastating diseases, including hepatitis, yel...

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Detalles Bibliográficos
Autores principales: Vlachakis, Dimitrios, Koumandou, Vassiliki Lila, Kossida, Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2013
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646357/
https://www.ncbi.nlm.nih.gov/pubmed/23678398
http://dx.doi.org/10.7717/peerj.74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646357/
https://www.ncbi.nlm.nih.gov/pubmed/23678398
http://dx.doi.org/10.7717/peerj.74

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