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A C-terminal PDZ domain binding sequence is required for striatal distribution of the dopamine transporter

The dopamine transporter (DAT) mediates reuptake of dopamine from the synaptic cleft. The cellular mechanisms controlling DAT levels in striatal nerve terminals remain poorly understood. DAT contains a C-terminal PDZ (PSD-95/Discs-large/ZO-1) domain binding sequence believed to bind synaptic scaffol...

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Detalles Bibliográficos
Autores principales: Rickhag, Mattias, Hansen, Freja Herborg, Sørensen, Gunnar, Strandfelt, Kristine Nørgaard, Andresen, Bjørn, Gotfryd, Kamil, Madsen, Kenneth L., Vestergaard-Klewe, Ib, Ammendrup-Johnsen, Ina, Eriksen, Jacob, Füchtbauer, Ernst-Martin, Gomeza, Jesus, Woldbye, David P.D., Wörtwein, Gitta, Gether, Ulrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646413/
https://www.ncbi.nlm.nih.gov/pubmed/23481388
http://dx.doi.org/10.1038/ncomms2568