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Comparison of apoA-I helical structure and stability in discoidal and spherical HDL particles by HX and mass spectrometry

Elucidation of apoA-I secondary structure in spherical plasma HDL particles is essential for understanding HDL structure and function at the molecular level. To provide this information, we have applied hydrogen exchange (HX) and mass spectrometry methods to compare apoA-I secondary structure in dis...

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Detalles Bibliográficos
Autores principales: Chetty, Palaniappan Sevugan, Nguyen, David, Nickel, Margaret, Lund-Katz, Sissel, Mayne, Leland, Englander, S. Walter, Phillips, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646460/
https://www.ncbi.nlm.nih.gov/pubmed/23580759
http://dx.doi.org/10.1194/jlr.M034785