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DNMT1 genetic polymorphisms affect breast cancer risk in the central European Caucasian population
INTRODUCTION: DNA methylation of CpG islands within the promoter region of genes is an epigenetic modification with an important role in the development of cancer and it is typically mediated by DNA methyltransferases (DNMTs). In cancer cells, global hypomethylation of the genome as a whole and regi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646668/ https://www.ncbi.nlm.nih.gov/pubmed/23638630 http://dx.doi.org/10.1186/1868-7083-5-7 |