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DNMT1 genetic polymorphisms affect breast cancer risk in the central European Caucasian population

INTRODUCTION: DNA methylation of CpG islands within the promoter region of genes is an epigenetic modification with an important role in the development of cancer and it is typically mediated by DNA methyltransferases (DNMTs). In cancer cells, global hypomethylation of the genome as a whole and regi...

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Detalles Bibliográficos
Autores principales:	Kullmann, Kathrin, Deryal, Mustafa, Ong, Mei Fang, Schmidt, Werner, Mahlknecht, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Case Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646668/ https://www.ncbi.nlm.nih.gov/pubmed/23638630 http://dx.doi.org/10.1186/1868-7083-5-7

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