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Effect of Signal Peptide on Stability and Folding of Escherichia coli Thioredoxin

The signal peptide plays a key role in targeting and membrane insertion of secretory and membrane proteins in both prokaryotes and eukaryotes. In E. coli, recombinant proteins can be targeted to the periplasmic space by fusing naturally occurring signal sequences to their N-terminus. The model prote...

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Detalles Bibliográficos
Autores principales: Singh, Pranveer, Sharma, Likhesh, Kulothungan, S. Rajendra, Adkar, Bharat V., Prajapati, Ravindra Singh, Ali, P. Shaik Syed, Krishnan, Beena, Varadarajan, Raghavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646739/
https://www.ncbi.nlm.nih.gov/pubmed/23667620
http://dx.doi.org/10.1371/journal.pone.0063442