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Effect of Signal Peptide on Stability and Folding of Escherichia coli Thioredoxin
The signal peptide plays a key role in targeting and membrane insertion of secretory and membrane proteins in both prokaryotes and eukaryotes. In E. coli, recombinant proteins can be targeted to the periplasmic space by fusing naturally occurring signal sequences to their N-terminus. The model prote...
Autores principales: | Singh, Pranveer, Sharma, Likhesh, Kulothungan, S. Rajendra, Adkar, Bharat V., Prajapati, Ravindra Singh, Ali, P. Shaik Syed, Krishnan, Beena, Varadarajan, Raghavan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646739/ https://www.ncbi.nlm.nih.gov/pubmed/23667620 http://dx.doi.org/10.1371/journal.pone.0063442 |
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