Cyclooxygenase-2 Inhibition Blocks M2 Macrophage Differentiation and Suppresses Metastasis in Murine Breast Cancer Model

Tumor cells are often associated with abundant macrophages that resemble the alternatively activated M2 subset. Tumor-associated macrophages (TAMs) inhibit anti-tumor immune responses and promote metastasis. Cyclooxygenase-2 (COX-2) inhibition is known to prevent breast cancer metastasis. This study...

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Detalles Bibliográficos
Autores principales: Na, Yi-Rang, Yoon, Yi-Na, Son, Da-In, Seok, Seung-Hyeok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646746/
https://www.ncbi.nlm.nih.gov/pubmed/23667623
http://dx.doi.org/10.1371/journal.pone.0063451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646746/
https://www.ncbi.nlm.nih.gov/pubmed/23667623
http://dx.doi.org/10.1371/journal.pone.0063451

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