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Targeting Human MicroRNA Genes Using Engineered Tal-Effector Nucleases (TALENs)

MicroRNAs (miRNAs) have quickly emerged as important regulators of mammalian physiology owing to their precise control over the expression of critical protein coding genes. Despite significant progress in our understanding of how miRNAs function in mice, there remains a fundamental need to be able t...

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Detalles Bibliográficos
Autores principales: Hu, Ruozhen, Wallace, Jared, Dahlem, Timothy J., Grunwald, David Jonah, O'Connell, Ryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646762/
https://www.ncbi.nlm.nih.gov/pubmed/23667577
http://dx.doi.org/10.1371/journal.pone.0063074