The Natural Human IgM Antibody PAT-SM6 Induces Apoptosis in Primary Human Multiple Myeloma Cells by Targeting Heat Shock Protein GRP78

In contrast to other haematological malignancies, targeted immunotherapy has not entered standard treatment regimens for de novo or relapsed multiple myeloma (MM) yet. While a number of IgG-formatted monoclonal antibodies are currently being evaluated in clinical trials in MM, our study aimed to inv...

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Detalles Bibliográficos
Autores principales: Rasche, Leo, Duell, Johannes, Morgner, Charlotte, Chatterjee, Manik, Hensel, Frank, Rosenwald, Andreas, Einsele, Hermann, Topp, Max S., Brändlein, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646784/
https://www.ncbi.nlm.nih.gov/pubmed/23667612
http://dx.doi.org/10.1371/journal.pone.0063414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646784/
https://www.ncbi.nlm.nih.gov/pubmed/23667612
http://dx.doi.org/10.1371/journal.pone.0063414

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