Regulation of Immune Responsiveness In Vivo by Disrupting an Early T-Cell Signaling Event Using a Cell-Permeable Peptide

The inducible T cell kinase (ITK) regulates type 2 (Th2) cytokines that provide defense against certain parasitic and bacterial infections and are involved in the pathogenesis of lung inflammation such as allergic asthma. Activation of ITK requires the interaction of its SH3 domain with the poly-pro...

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Detalles Bibliográficos
Autores principales: Guimond, David M., Cam, Nicholas R., Hirve, Nupura, Duan, Wei, Lambris, John D., Croft, Michael, Tsoukas, Constantine D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646824/
https://www.ncbi.nlm.nih.gov/pubmed/23667652
http://dx.doi.org/10.1371/journal.pone.0063645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646824/
https://www.ncbi.nlm.nih.gov/pubmed/23667652
http://dx.doi.org/10.1371/journal.pone.0063645

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