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Metabolic States Following Accumulation of Intracellular Aggregates: Implications for Neurodegenerative Diseases
The formation of intracellular aggregates is a common etiology of several neurodegenerative diseases. Mitochondrial defects and oxidative stress has been pointed as the major mechanistic links between the accumulation of intracellular aggregates and cell death. In this work we propose a “metabolic c...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646825/ https://www.ncbi.nlm.nih.gov/pubmed/23667676 http://dx.doi.org/10.1371/journal.pone.0063822 |