Fli-1 Overexpression in Hematopoietic Progenitors Deregulates T Cell Development and Induces Pre-T Cell Lymphoblastic Leukaemia/Lymphoma

The Ets transcription factor Fli-1 is preferentially expressed in hematopoietic tissues and cells, including immature T cells, but the role of Fli-1 in T cell development has not been closely examined. To address this we retrovirally overexpressed Fli-1 in various in vitro and in vivo settings and a...

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Detalles Bibliográficos
Autores principales: Smeets, Monique F. M. A., Chan, Angela C., Dagger, Samantha, Bradley, Cara K., Wei, Andrew, Izon, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646842/
https://www.ncbi.nlm.nih.gov/pubmed/23667468
http://dx.doi.org/10.1371/journal.pone.0062346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646842/
https://www.ncbi.nlm.nih.gov/pubmed/23667468
http://dx.doi.org/10.1371/journal.pone.0062346

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