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κ-Opioid Receptor Stimulation Improves Endothelial Function in Hypoxic Pulmonary Hypertension
The present study was designed to investigate the effect of κ-opioid receptor stimulation with U50,488H on endothelial function and underlying mechanism in rats with hypoxic pulmonary hypertension (HPH). Chronic hypoxia-induced HPH was simulated by exposing the rats to 10% oxygen for 2 wk. After hyp...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646880/ https://www.ncbi.nlm.nih.gov/pubmed/23667430 http://dx.doi.org/10.1371/journal.pone.0060850 |