The Carboxy-Terminal αN Helix of the Archaeal XerA Tyrosine Recombinase Is a Molecular Switch to Control Site-Specific Recombination

Tyrosine recombinases are conserved in the three kingdoms of life. Here we present the first crystal structure of a full-length archaeal tyrosine recombinase, XerA from Pyrococcus abyssi, at 3.0 Å resolution. In the absence of DNA substrate XerA crystallizes as a dimer where each monomer displays a...

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Detalles Bibliográficos
Autores principales: Serre, Marie-Claude, El Arnaout, Toufic, Brooks, Mark A., Durand, Dominique, Lisboa, Johnny, Lazar, Noureddine, Raynal, Bertrand, van Tilbeurgh, Herman, Quevillon-Cheruel, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646895/
https://www.ncbi.nlm.nih.gov/pubmed/23667562
http://dx.doi.org/10.1371/journal.pone.0063010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646895/
https://www.ncbi.nlm.nih.gov/pubmed/23667562
http://dx.doi.org/10.1371/journal.pone.0063010

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