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Generation of mRx-Cre Transgenic Mouse Line for Efficient Conditional Gene Deletion in Early Retinal Progenitors

During mouse eye development, all retinal cell types are generated from the population of retina-committed progenitors originating from the neuroepithelium of the optic vesicle. Conditional gene inactivation provides an efficient tool for studying the genetic basis of the developing retina; however,...

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Detalles Bibliográficos
Autores principales: Klimova, Lucie, Lachova, Jitka, Machon, Ondrej, Sedlacek, Radislav, Kozmik, Zbynek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646923/
https://www.ncbi.nlm.nih.gov/pubmed/23667567
http://dx.doi.org/10.1371/journal.pone.0063029