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Increased Tc22 and Treg/CD8 Ratio Contribute to Aggressive Growth of Transplant Associated Squamous Cell Carcinoma

Immune suppressed organ transplant recipients suffer increased morbidity and mortality from primary cutaneous SCC. We studied tumor microenvironment in transplant-associated SCC (TSCC), immune-competent SCC and normal skin by IHC, IF and RT-PCR on surgical discard. We determined T cell polarization...

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Detalles Bibliográficos
Autores principales: Zhang, Shali, Fujita, Hideki, Mitsui, Hiroshi, Yanofsky, Valerie R., Fuentes-Duculan, Judilyn, Pettersen, Julia S., Suárez-Fariñas, Mayte, Gonzalez, Juana, Wang, Claire Q. F., Krueger, James G., Felsen, Diane, Carucci, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646982/
https://www.ncbi.nlm.nih.gov/pubmed/23667456
http://dx.doi.org/10.1371/journal.pone.0062154