The Sensitivity of Diffuse Large B-Cell Lymphoma Cell Lines to Histone Deacetylase Inhibitor-Induced Apoptosis Is Modulated by BCL-2 Family Protein Activity

BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) is a genetically heterogeneous disease and this variation can often be used to explain the response of individual patients to chemotherapy. One cancer therapeutic approach currently in clinical trials uses histone deacetylase inhibitors (HDACi’s) as...

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Detalles Bibliográficos
Autores principales: Thompson, Ryan C., Vardinogiannis, Iosif, Gilmore, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647059/
https://www.ncbi.nlm.nih.gov/pubmed/23667527
http://dx.doi.org/10.1371/journal.pone.0062822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647059/
https://www.ncbi.nlm.nih.gov/pubmed/23667527
http://dx.doi.org/10.1371/journal.pone.0062822

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