Early Onset Pre-Eclampsia Is Associated with Altered DNA Methylation of Cortisol-Signalling and Steroidogenic Genes in the Placenta

Placental cortisol is inactivated in normotensive pregnancies, but is frequently present in pre-eclampsia associated placentae. Since glucocorticoids are strongly associated with the programming of long-term health, we assessed DNA methylation of genes involved in cortisol signalling and bioavailabi...

Descripción completa

Detalles Bibliográficos
Autores principales: Hogg, Kirsten, Blair, John D., McFadden, Deborah E., von Dadelszen, Peter, Robinson, Wendy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647069/
https://www.ncbi.nlm.nih.gov/pubmed/23667551
http://dx.doi.org/10.1371/journal.pone.0062969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647069/
https://www.ncbi.nlm.nih.gov/pubmed/23667551
http://dx.doi.org/10.1371/journal.pone.0062969

Ejemplares similares