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Early Onset Pre-Eclampsia Is Associated with Altered DNA Methylation of Cortisol-Signalling and Steroidogenic Genes in the Placenta

Placental cortisol is inactivated in normotensive pregnancies, but is frequently present in pre-eclampsia associated placentae. Since glucocorticoids are strongly associated with the programming of long-term health, we assessed DNA methylation of genes involved in cortisol signalling and bioavailabi...

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Detalles Bibliográficos
Autores principales:	Hogg, Kirsten, Blair, John D., McFadden, Deborah E., von Dadelszen, Peter, Robinson, Wendy P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647069/ https://www.ncbi.nlm.nih.gov/pubmed/23667551 http://dx.doi.org/10.1371/journal.pone.0062969

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