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mPGES-1 and prostaglandin E(2): vital role in inflammation, hypoxic response, and survival

BACKGROUND: Apnea associated with infection and inflammation is a major medical concern in preterm infants. Prostaglandin E(2) (PGE(2)) serves as a critical mediator between infection and apnea. We hypothesize that alteration of the microsomal PGE synthase-1 (mPGES-1) PGE(2) pathway influences respi...

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Detalles Bibliográficos
Autores principales: Siljehav, Veronica, Olsson Hofstetter, Annika, Jakobsson, Per-Johan, Herlenius, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647218/
https://www.ncbi.nlm.nih.gov/pubmed/22926547
http://dx.doi.org/10.1038/pr.2012.119