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Targeting PI3K in Cancer: Any Good News?

The phosphatidylinositol 3-kinase (PI3K) signaling pathway regulates several cellular processes and it’s one of the most frequently deregulated pathway in human tumors. Given its prominent role in cancer, there is great interest in the development of inhibitors able to target several members of PI3K...

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Detalles Bibliográficos
Autores principales: Martini, Miriam, Ciraolo, Elisa, Gulluni, Federico, Hirsch, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647219/
https://www.ncbi.nlm.nih.gov/pubmed/23658859
http://dx.doi.org/10.3389/fonc.2013.00108