MicroRNA‐210 Decreases heme Levels by Targeting Ferrochelatase in Cardiomyocytes

BACKGROUND: MicroRNA‐210 (miR‐210) increases in hypoxia and regulates mitochondrial respiration through modulation of iron‐sulfur cluster assembly proteins (ISCU1/2), a protein that is involved in Fe/S cluster synthesis. However, it is not known how miR‐210 affects cellular iron levels or production...

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Detalles Bibliográficos
Autores principales: Qiao, Aijun, Khechaduri, Arineh, Kannan Mutharasan, R., Wu, Rongxue, Nagpal, Varun, Ardehali, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647255/
https://www.ncbi.nlm.nih.gov/pubmed/23608607
http://dx.doi.org/10.1161/JAHA.113.000121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647255/
https://www.ncbi.nlm.nih.gov/pubmed/23608607
http://dx.doi.org/10.1161/JAHA.113.000121

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