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MicroRNA‐210 Decreases heme Levels by Targeting Ferrochelatase in Cardiomyocytes
BACKGROUND: MicroRNA‐210 (miR‐210) increases in hypoxia and regulates mitochondrial respiration through modulation of iron‐sulfur cluster assembly proteins (ISCU1/2), a protein that is involved in Fe/S cluster synthesis. However, it is not known how miR‐210 affects cellular iron levels or production...
Autores principales: | Qiao, Aijun, Khechaduri, Arineh, Kannan Mutharasan, R., Wu, Rongxue, Nagpal, Varun, Ardehali, Hossein |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647255/ https://www.ncbi.nlm.nih.gov/pubmed/23608607 http://dx.doi.org/10.1161/JAHA.113.000121 |
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