Cathepsin‐L Ameliorates Cardiac Hypertrophy Through Activation of the Autophagy–Lysosomal Dependent Protein Processing Pathways

BACKGROUND: Autophagy is critical in the maintenance of cellular protein quality control, the final step of which involves the fusion of autophagosomes with lysosomes. Cathepsin‐L (CTSL) is a key member of the lysosomal protease family that is expressed in the murine and human heart, and it may play...

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Detalles Bibliográficos
Autores principales: Sun, Mei, Ouzounian, Maral, de Couto, Geoffrey, Chen, Manyin, Yan, Ran, Fukuoka, Masahiro, Li, Guohua, Moon, Mark, Liu, Youan, Gramolini, Anthony, Wells, George J., Liu, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647266/
https://www.ncbi.nlm.nih.gov/pubmed/23608608
http://dx.doi.org/10.1161/JAHA.113.000191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647266/
https://www.ncbi.nlm.nih.gov/pubmed/23608608
http://dx.doi.org/10.1161/JAHA.113.000191

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