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CD14 Directs Adventitial Macrophage Precursor Recruitment: Role in Early Abdominal Aortic Aneurysm Formation

BACKGROUND: Recruitment of macrophage precursors to the adventitia plays a key role in the pathogenesis of abdominal aortic aneurysms (AAAs), but molecular mechanisms remain undefined. The innate immune signaling molecule CD14 was reported to be upregulated in adventitial macrophages in a murine mod...

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Detalles Bibliográficos
Autores principales: Blomkalns, Andra L., Gavrila, Daniel, Thomas, Manesh, Neltner, Bonnie S., Blanco, Victor M., Benjamin, Stephanie B., McCormick, Michael L., Stoll, Lynn L., Denning, Gerene M., Collins, Sean P., Qin, Zhenyu, Daugherty, Alan, Cassis, Lisa A., Thompson, Robert W., Weiss, Robert M., Lindower, Paul D., Pinney, Susan M., Chatterjee, Tapan, Weintraub, Neal L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647288/
https://www.ncbi.nlm.nih.gov/pubmed/23537804
http://dx.doi.org/10.1161/JAHA.112.000065