Angiotensin-Converting Enzyme 2 Deficiency Aggravates Glucose Intolerance via Impairment of Islet Microvascular Density in Mice with High-Fat Diet

The aim of this study was to evaluate the effects of angiotensin-converting enzyme 2 (ACE2) on glucose homeostasis and islet function in mice. Male wildtype (WT) and ACE2 knockout (ACE2 KO) mice were divided into chow diet group and long-term high-fat diet (HFD) group. After 16 weeks of feeding, the...

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Detalles Bibliográficos
Autores principales: Yuan, Li, Wang, Ying, Lu, Chunli, Li, Xiaoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647559/
https://www.ncbi.nlm.nih.gov/pubmed/23671869
http://dx.doi.org/10.1155/2013/405284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647559/
https://www.ncbi.nlm.nih.gov/pubmed/23671869
http://dx.doi.org/10.1155/2013/405284

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