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The Spontaneously Diabetic Torii Rat: An Animal Model of Nonobese Type 2 Diabetes with Severe Diabetic Complications

The Spontaneously Diabetic Torii (SDT) rat is an inbred strain of Sprague-Dawley rat and recently is established as a nonobese model of type 2 diabetes (T2D). Male SDT rats show high plasma glucose levels (over 700 mg/dL) by 20 weeks. Male SDT rats show pancreatic islet histopathology, including hem...

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Detalles Bibliográficos
Autores principales: Sasase, Tomohiko, Ohta, Takeshi, Masuyama, Taku, Yokoi, Norihide, Kakehashi, Akihiro, Shinohara, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647578/
https://www.ncbi.nlm.nih.gov/pubmed/23691526
http://dx.doi.org/10.1155/2013/976209